Year Item Type Full Text

Article

A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates in Nigeria. (2023) Adegbola, Adebanjo J; Ijarotimi, Omotade A; Ubom, Akaninyene E; Adesoji, Bukola A; Babalola, Olajide E; Hocke, Emma F; Hansson, Helle; Mousa, Andria; Bolaji, Oluseye O; Alifrangis, Michael; Roper, Cally

Modelling the impact of intermittent preventive treatment for malaria on selection pressure for drug resistance. (2007) Alexander, Neal; Sutherland, Colin; Roper, Cally; Cissé, Badara; Schellenberg, David

Asymptomatic Plasmodium falciparum infections and determinants of carriage in a seasonal malaria chemoprevention setting in Northern Cameroon and south Senegal (Kedougou). (2024) Ali, Innocent M; Manga, Isaac A; Nji, Akindeh M; Tchuenkam, Valery P; Neba, Peter Thelma Ngwa; Achu, Dorothy F; Bigoga, Jude D; Faye, Babacar; Roper, Cally; Sutherland, Colin J; Mbacham, Wilfred F

A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent assay-based technology. (2005) Alifrangis, Michael; Enosse, Sonia; Pearce, Richard; Drakeley, Chris; Roper, Cally; Khalil, Insaf F; Nkya, Watoky Mmm; Rønn, Anita M; Theander, Thor G; Bygbjerg, Ib C

Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia. (2014) Alifrangis, Michael; Nag, Sidsel; Schousboe, Mette L; Ishengoma, Deus; Lusingu, John; Pota, Hirva; Kavishe, Reginald A; Pearce, Richard; Ord, Rosalynn; Lynch, Caroline; Dejene, Seyoum; Cox, Jonathan; Rwakimari, John; Minja, Daniel TR; Lemnge, Martha M; Roper, Cally

The origins and spread of antimalarial drug resistance: lessons for policy makers. (2005) Anderson, Tim JC; Roper, Cally

Increased gametocytemia after treatment: an early parasitological indicator of emerging sulfadoxine-pyrimethamine resistance in falciparum malaria. (2008) Barnes, Karen I; Little, Francesca; Mabuza, Aaron; Mngomezulu, Nicros; Govere, John; Durrheim, David; Roper, Cally; Watkins, Bill; White, Nicholas J

Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development. (2018) Benavente, Ernest Diez; Oresegun, Damilola R; de Sessions, Paola Florez; Walker, Eloise M; Roper, Cally; Dombrowski, Jamille G; de Souza, Rodrigo M; Marinho, Claudio RF; Sutherland, Colin J; Hibberd, Martin L; Mohareb, Fady; Baker, David A; Clark, Taane G; Campino, Susana

A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line. (2017) Benavente, Ernest Diez; de Sessions, Paola Florez; Moon, Robert W; Grainger, Munira; Holder, Anthony A; Blackman, Michael J; Roper, Cally; Drakeley, Christopher J; Pain, Arnab; Sutherland, Colin J; Hibberd, Martin L; Campino, Susana; Clark, Taane G

Population genetic analysis of the Plasmodium falciparum erythrocyte binding antigen-175 (eba-175) gene. (2001) Binks, RH; Baum, J; Oduola, AM; Arnot, DE; Babiker, HA; Kremsner, PG; Roper, C; Greenwood, BM; Conway, DJ

Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N'Zérékoré. (2007) Bonnet, Maryline; Roper, Cally; Félix, Martine; Coulibaly, Léonie; Kankolongo, Gabriel Mufuta; Guthmann, Jean Paul

Evolutionary genetics: microarrays and species origins. (2005) Butlin, Roger; Roper, Cally

Frequency of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase markers in six Districts in Zambia. (2007) Chanda, P; Hawela, M; Mharakurwa, S; Shinondo, C; Roper, C; Pota, H

Influence of malaria transmission intensity and the 581G mutation on the efficacy of intermittent preventive treatment in pregnancy: systematic review and meta-analysis. (2015) Chico, R Matthew; Cano, Jorge; Ariti, Cono; Collier, Timothy J; Chandramohan, Daniel; Roper, Cally; Greenwood, Brian

Extreme geographical fixation of variation in the Plasmodium falciparum gamete surface protein gene Pfs48/45 compared with microsatellite loci. (2001) Conway, DJ; Machado, RL; Singh, B; Dessert, P; Mikes, ZS; Povoa, MM; Oduola, AM; Roper, C

Origin and dissemination across the Colombian Andes mountain range of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum. (2010) Corredor, Vladimir; Murillo, Claribel; Echeverry, Diego F; Benavides, Julie; Pearce, Richard J; Roper, Cally; Guerra, Angela P; Osorio, Lyda

Sustained use of insecticide-treated curtains is not associated with greater circulation of drug-resistant malaria parasites, or with higher risk of treatment failure among children with uncomplicated malaria in Burkina Faso. (2007) Diallo, Diadier A; Sutherland, Colin; Nebié, Issa; Konaté, Amadou T; Ord, Rosalynn; Pota, Hirva; Roper, Cally; Ilboudo-Sanogo, Edith; Greenwood, Brian M; Cousens, Simon N

A molecular barcode to inform the geographical origin and transmission dynamics of Plasmodium vivax malaria. (2020) Diez Benavente, Ernest; Campos, Monica; Phelan, Jody; Nolder, Debbie; Dombrowski, Jamille G; Marinho, Claudio RF; Sriprawat, Kanlaya; Taylor, Aimee R; Watson, James; Roper, Cally; Nosten, Francois; Sutherland, Colin J; Campino, Susana; Clark, Taane G

Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations. (2017) Diez Benavente, Ernest; Florez de Sessions, Paola; Moon, Robert W; Holder, Anthony A; Blackman, Michael J; Roper, Cally; Drakeley, Christopher J; Pain, Arnab; Sutherland, Colin J; Hibberd, Martin L; Campino, Susana; Clark, Taane G

Genomic variation in Plasmodium vivax malaria reveals regions under selective pressure. (2017) Diez Benavente, Ernest; Ward, Zoe; Chan, Wilson; Mohareb, Fady R; Sutherland, Colin J; Roper, Cally; Campino, Susana; Clark, Taane G

Associations between alpha+-thalassemia and Plasmodium falciparum malarial infection in northeastern Tanzania. (2007) Enevold, Anders; Alifrangis, Michael; Sanchez, Juan J; Carneiro, Ilona; Roper, Cally; Børsting, Claus; Lusingu, John; Vestergaard, Lasse S; Lemnge, Martha M; Morling, Niels; Riley, Eleanor; Drakeley, Chris J

Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum. (2013) Flegg, Jennifer A; Patil, Anand P; Venkatesan, Meera; Roper, Cally; Naidoo, Inbarani; Hay, Simon I; Sibley, Carol Hopkins; Guerin, Philippe J

High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581. (2009) Gesase, Samwel; Gosling, Roly D; Hashim, Ramadhan; Ord, Rosalynn; Naidoo, Inbarani; Madebe, Rashid; Mosha, Jacklin F; Joho, Angel; Mandia, Victor; Mrema, Hedwiga; Mapunda, Ephraim; Savael, Zacharia; Lemnge, Martha; Mosha, Frank W; Greenwood, Brian; Roper, Cally; Chandramohan, Daniel

Surveillance of travellers: an additional tool for tracking antimalarial drug resistance in endemic countries. (2013) Gharbi, Myriam; Flegg, Jennifer A; Pradines, Bruno; Berenger, Ako; Ndiaye, Magatte; Djimdé, Abdoulaye A; Roper, Cally; Hubert, Véronique; Kendjo, Eric; Venkatesan, Meera; Brasseur, Philippe; Gaye, Oumar; Offianan, André T; Penali, Louis; Le Bras, Jacques; Guérin, Philippe J; Members of the French National Reference Center for Imported Mal

Genetic diversity of next generation antimalarial targets: A baseline for drug resistance surveillance programmes. (2017) Gomes, Ana Rita; Ravenhall, Matt; Benavente, Ernest Diez; Talman, Arthur; Sutherland, Colin; Roper, Cally; Clark, Taane G; Campino, Susana

Corrigendum to "Genetic diversity of next generation antimalarial targets: A baseline for drug resistance surveillance programmes" [Int. J. Parasitol. Drugs and Drug Resist. 7 (2017) 174-180]. (2017) Gomes, Ana Rita; Ravenhall, Matt; Benavente, Ernest Diez; Talman, Arthur; Sutherland, Colin; Roper, Cally; Clark, Taane G; Campino, Susana

Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine-pyrimethamine and parasite resistance. (2010) Griffin, Jamie T; Cairns, Matthew; Ghani, Azra C; Roper, Cally; Schellenberg, David; Carneiro, Ilona; Newman, Robert D; Grobusch, Martin P; Greenwood, Brian; Chandramohan, Daniel; Gosling, Roly D

Selective whole genome amplification of Plasmodium malariae DNA from clinical samples reveals insights into population structure. (2020) Ibrahim, Amy; Diez Benavente, Ernest; Nolder, Debbie; Proux, Stephane; Higgins, Matthew; Muwanguzi, Julian; Gomez Gonzalez, Paula Josefina; Fuehrer, Hans-Peter; Roper, Cally; Nosten, Francois; Sutherland, Colin; Clark, Taane G; Campino, Susana

Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges. (2019) Ishengoma, Deus S; Saidi, Queen; Sibley, Carol H; Roper, Cally; Alifrangis, Michael

Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976-78. (2017) Jovel, Irina T; Björkman, Anders; Roper, Cally; Mårtensson, Andreas; Ursing, Johan

Molecular monitoring of Plasmodium falciparum super-resistance to sulfadoxine-pyrimethamine in Tanzania. (2016) Kavishe, Reginald A; Kaaya, Robert D; Nag, Sidsel; Krogsgaard, Camilla; Notland, Jakob Ginsbak; Kavishe, Adellaida A; Ishengoma, Deus; Roper, Cally; Alifrangis, Michael

Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania. (2014) Kavishe, Reginald A; Paulo, Petro; Kaaya, Robert D; Kalinga, Akili; van Zwetselaar, Marco; Chilongola, Jaffu; Roper, Cally; Alifrangis, Michael

Intermittent preventive therapy for malaria during pregnancy using 2 vs 3 or more doses of sulfadoxine-pyrimethamine and risk of low birth weight in Africa: systematic review and meta-analysis. (2013) Kayentao, Kassoum; Garner, Paul; van Eijk, Anne Maria; Naidoo, Inbarani; Roper, Cally; Mulokozi, Abdunoor; MacArthur, John R; Luntamo, Mari; Ashorn, Per; Doumbo, Ogobara K; ter Kuile, Feiko O

Association between recent internal travel and malaria in Ugandan highland and highland fringe areas. (2015) Lynch, Caroline A; Bruce, Jane; Bhasin, Amit; Roper, Cally; Cox, Jonathan; Abeku, Tarekegn A

Application of Serological Tools and Spatial Analysis to Investigate Malaria Transmission Dynamics in Highland Areas of Southwest Uganda. (2016) Lynch, Caroline A; Cook, Jackie; Nanyunja, Sarah; Bruce, Jane; Bhasin, Amit; Drakeley, Chris; Roper, Cally; Pearce, Richard; Rwakimari, John B; Abeku, Tarekegn A; Corran, Patrick; Cox, Jonathan

Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study. (2017) Lynch, Caroline A; Pearce, Richard; Pota, Hirva; Egwang, Connie; Egwang, Thomas; Bhasin, Amit; Cox, Jonathan; Abeku, Tarekegn A; Roper, Cally

Emergence of a dhfr mutation conferring high-level drug resistance in Plasmodium falciparum populations from southwest Uganda. (2008) Lynch, Caroline; Pearce, Richard; Pota, Hirva; Cox, Jonathan; Abeku, Tarekegn A; Rwakimari, John; Naidoo, Inbarani; Tibenderana, James; Roper, Cally

The transit phase of migration: circulation of malaria and its multidrug-resistant forms in Africa. (2011) Lynch, Caroline; Roper, Cally

Molecular monitoring of resistant dhfr and dhps allelic haplotypes in Morogoro and Mvomero districts in south eastern Tanzania. (2011) Malisa, A; Pearce, R; Abdullah, S; Mutayoba, B; Mshinda, H; Kachur, P; Bloland, P; Roper, C

Drug coverage in treatment of malaria and the consequences for resistance evolution--evidence from the use of sulphadoxine/pyrimethamine. (2010) Malisa, Allen L; Pearce, Richard J; Abdulla, Salim; Mshinda, Hassan; Kachur, Patrick S; Bloland, Peter; Roper, Cally

The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination. (2011) Malisa, Allen L; Pearce, Richard J; Mutayoba, Ben M; Abdullah, Salim; Mshinda, Hassan; Kachur, Patrick S; Bloland, Peter; Roper, Cally

Media, health workers, and policy makers' relationship and their impact on antimalarial policy adoption: a population genetics perspective. (2011) Malisa, Allen; Pearce, Richard; Mutayoba, Benezeth; Abdullah, Salim; Mshinda, Hassan; Kachur, Patrick; Bloland, Peter; Roper, Cally

Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania. (2011) Manjurano, Alphaxard; Okell, Lucy; Lukindo, Tedson; Reyburn, Hugh; Olomi, Raimos; Roper, Cally; Clark, Taane G; Joseph, Sarah; Riley, Eleanor M; Drakeley, Chris

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. (2012) Manske, Magnus; Miotto, Olivo; Campino, Susana; Auburn, Sarah; Almagro-Garcia, Jacob; Maslen, Gareth; O'Brien, Jack; Djimde, Abdoulaye; Doumbo, Ogobara; Zongo, Issaka; Ouedraogo, Jean-Bosco; Michon, Pascal; Mueller, Ivo; Siba, Peter; Nzila, Alexis; Borrmann, Steffen; Kiara, Steven M; Marsh, Kevin; Jiang, Hongying; Su, Xin-Zhuan; Amaratunga, Chanaki; Fairhurst, Rick; Socheat, Duong; Nosten, Francois; Imwong, Mallika; White, Nicholas J; Sanders, Mandy; Anastasi, Elisa; Alcock, Dan; Drury, Eleanor; Oyola, Samuel; Quail, Michael A; Turner, Daniel J; Ruano-Rubio, Valentin; Jyothi, Dushyanth; Amenga-Etego, Lucas; Hubbart, Christina; Jeffreys, Anna; Rowlands, Kate; Sutherland, Colin; Roper, Cally; Mangano, Valentina; Modiano, David; Tan, John C; Ferdig, Michael T; Amambua-Ngwa, Alfred; Conway, David J; Takala-Harrison, Shannon; Plowe, Christopher V; Rayner, Julian C; Rockett, Kirk A; Clark, Taane G; Newbold, Chris I; Berriman, Matthew; MacInnis, Bronwyn; Kwiatkowski, Dominic P

Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a three-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine plus amodiaquine versus artesunate monotherapy among asymptomatic children 3-5 years of age in Cameroon. (2024) Martinez-Vega, Rosario; Mbacham, Wilfred Fon; Ali, Innocent; Nji, Akindeh; Mousa, Andria; Beshir, Khalid B; Chopo-Pizarro, Ana; Kaur, Harparkash; Okell, Lucy; Hansson, Helle; Hocke, Emma Filtenborg; Alifrangis, Michael; Gosling, Roland; Roper, Cally; Sutherland, Colin; Chico, R Matthew

Efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated Plasmodium falciparum malaria in children in Cameroon at the time of policy change to artemisinin-based combination therapy. (2010) Mbacham, Wilfred F; Evehe, Marie-Solange B; Netongo, Palmer M; Ateh, Isabel A; Mimche, Patrice N; Ajua, Anthony; Nji, Akindeh M; Irenee, Domkam; Echouffo-Tcheugui, Justin B; Tawe, Bantar; Hallett, Rachel; Roper, Cally; Targett, Geoffrey; Greenwood, Brian

Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola. (2009) Menegon, Michela; Pearce, Richard J; Inojosa, Walter O; Pisani, Vincenzo; Abel, Paulo M; Matondo, Alexandre; Bisoffi, Zeno; Majori, Giancarlo; Ord, Rosalynn; Warhurst, David C; Roper, Cally; Severini, Carlo

Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo. (2023) Mesia Kahunu, Gauthier; Wellmann Thomsen, Sarah; Wellmann Thomsen, Louise; Muhindo Mavoko, Hypolite; Mitashi Mulopo, Patrick; Filtenborg Hocke, Emma; Mandoko Nkoli, Papy; Baraka, Vito; Minja, Daniel TR; Mousa, Andria; Roper, Cally; Mbongi Moke, Destin; Mumba Ngoyi, Dieudonné; Mukomena Sompwe, Eric; Muyembe Tanfum, Jean Jacques; Hansson, Helle; Alifrangis, Michael

Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania. (2013) Mohammed, Asia; Ndaro, Arnold; Kalinga, Akili; Manjurano, Alphaxard; Mosha, Jackline F; Mosha, Dominick F; van Zwetselaar, Marco; Koenderink, Jan B; Mosha, Frank W; Alifrangis, Michael; Reyburn, Hugh; Roper, Cally; Kavishe, Reginald A

High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children. (2011) Mombo-Ngoma, Ghyslain; Oyakhirome, Sunny; Ord, Rosalynn; Gabor, Julian J; Greutélaers, Katja C; Profanter, Katharina; Greutélaers, Benedikt; Kurth, Florian; Lell, Bertrand; Kun, Jürgen FJ; Issifou, Saadou; Roper, Cally; Kremsner, Peter G; Grobusch, Martin P

Estimating the Impact of DHPS Mutations on Sulfadoxine-Pyrimethamine Protective Efficacy: A Pooled Analysis of Individual Patient Data and Implications for Malaria Chemoprevention in Sub-Saharan Africa. (2024) Mousa, Andria; Cuomo-Dannenburg, Gina; Thompson, Hayley A; Bell, David J; D'Alessandro, Umberto; Gosling, Roly; Nahum, Alain; Barnes, Karen; Raman, Jaishree; Workman, Lesley; Foo, Yong See; Flegg, Jennifer; Hocke, Emma F; Hansson, Helle; Chopo-Pizarro, Ana; Beshir, Khalid B; Alifrangis, Michael; Chico, R Matthew; Sutherland, Colin J; Okell, Lucy; Roper, Cally

Impact of dhps mutations on sulfadoxine-pyrimethamine protective efficacy and implications for malaria chemoprevention. (2025) Mousa, Andria; Cuomo-Dannenburg, Gina; Thompson, Hayley A; Bell, David J; D’Alessandro, Umberto; Gosling, Roly; Nahum, Alain; Barnes, Karen I; Raman, Jaishree; Workmann, Lesley; Foo, Yong See; Flegg, Jennifer A; Hocke, Emma Filtenborg; Hansson, Helle; Chopo-Pizarro, Ana; Beshir, Khalid B; Alifrangis, Michael; Chico, R Matthew; Sutherland, Colin J; Okell, Lucy C; Roper, Cally

Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology. (2024) Mousa, Andria; Cuomo-Dannenburg, Gina; Thompson, Hayley A; Chico, R Matthew; Beshir, Khalid B; Sutherland, Colin J; Schellenberg, David; Gosling, Roly; Alifrangis, Michael; Hocke, Emma Filtenborg; Hansson, Helle; Chopo-Pizarro, Ana; Mbacham, Wilfred F; Ali, Innocent M; Chaponda, Mike; Roper, Cally; Okell, Lucy C

Drug resistance maps to guide intermittent preventive treatment of malaria in African infants. (2011) Naidoo, Inbarani; Roper, Cally

Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum. (2010) Naidoo, Inbarani; Roper, Cally

Mapping 'partially resistant', 'fully resistant', and 'super resistant' malaria. (2013) Naidoo, Inbarani; Roper, Cally

Defining the origin of Plasmodium falciparum resistant dhfr isolates in Senegal. (2006) Ndiaye, D; Daily, JP; Sarr, O; Ndir, O; Gaye, O; Mboup, S; Roper, C; Wirth, DF

Molecular assays for antimalarial drug resistance surveillance: A target product profile. (2018) Nsanzabana, Christian; Ariey, Frederic; Beck, Hans-Peter; Ding, Xavier C; Kamau, Edwin; Krishna, Sanjeev; Legrand, Eric; Lucchi, Naomi; Miotto, Olivo; Nag, Sidsel; Noedl, Harald; Roper, Cally; Rosenthal, Philip J; Schallig, Henk DFH; Taylor, Steve M; Volkman, Sarah K; Gonzalez, Iveth J

Identification of Single-Nucleotide Polymorphisms in the Mitochondrial Genome and Kelch 13 Gene of Plasmodium falciparum in Different Geographical Populations. (2021) Nydahl, Tine Kliim; Ahorhorlu, Samuel Yao; Ndiaye, Magatte; Das, Manoj Kumar; Hansson, Helle; Bravo, Marina Crespo; Wang, Christian William; Lusingu, John; Theisen, Michael; Singh, Susheel Kumar; Singh, Subhash; Campino, Susana; Lund, Ole; Roper, Cally; Alifrangis, Michael

Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V. (2016) Oguike, Mary C; Falade, Catherine O; Shu, Elvis; Enato, Izehiuwa G; Watila, Ismaila; Baba, Ebenezer S; Bruce, Jane; Webster, Jayne; Hamade, Prudence; Meek, Sylvia; Chandramohan, Daniel; Sutherland, Colin J; Warhurst, David; Roper, Cally html

Mapping sulphadoxine-pyrimethamine-resistant Plasmodium falciparum malaria in infected humans and in parasite populations in Africa. (2017) Okell, Lucy C; Griffin, Jamie T; Roper, Cally

Emerging implications of policies on malaria treatment: genetic changes in the Pfmdr-1 gene affecting susceptibility to artemether-lumefantrine and artesunate-amodiaquine in Africa. (2018) Okell, Lucy C; Reiter, Lisa Malene; Ebbe, Lene Sandø; Baraka, Vito; Bisanzio, Donal; Watson, Oliver J; Bennett, Adam; Verity, Robert; Gething, Peter; Roper, Cally; Alifrangis, Michael

The polymorphic linker domain of pfmdr1 is associated with resistance-conferring mutations in Plasmodium falciparum populations from East and West Africa. (2013) Okombo, John; Zongo, Issaka; Gadalla, Nahla; Bousema, Teun; Beshir, Khalid B; Roper, Cally; Hallett, Rachel; Ochola-Oyier, Lynette Isabella; Sutherland, Colin J

Molecular determination of point mutation haplotypes in the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum in three districts of northern Tanzania. (2003) Pearce, Richard J; Drakeley, Chris; Chandramohan, Daniel; Mosha, Frank; Roper, Cally

A community-randomized evaluation of the effect of intermittent preventive treatment in infants on antimalarial drug resistance in southern Tanzania. (2013) Pearce, Richard J; Ord, Rosalynn; Kaur, Haprarksh; Lupala, Cecylia; Schellenberg, Joanna; Shirima, Kitzito; Manzi, Fatuma; Alonso, Pedro; Tanner, Marcel; Mshinda, Hassan; Roper, Cally; Schellenberg, David

Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria. (2009) Pearce, Richard J; Pota, Hirva; Evehe, Marie-Solange B; Bâ, El-Hadj; Mombo-Ngoma, Ghyslain; Malisa, Allen L; Ord, Rosalynn; Inojosa, Walter; Matondo, Alexandre; Diallo, Diadier A; Mbacham, Wilfred; van den Broek, Ingrid V; Swarthout, Todd D; Getachew, Asefaw; Dejene, Seyoum; Grobusch, Martin P; Njie, Fanta; Dunyo, Samuel; Kweku, Margaret; Owusu-Agyei, Seth; Chandramohan, Daniel; Bonnet, Maryline; Guthmann, Jean-Paul; Clarke, Sian; Barnes, Karen I; Streat, Elizabeth; Katokele, Stark T; Uusiku, Petrina; Agboghoroma, Chris O; Elegba, Olufunmilayo Y; Cissé, Badara; A-Elbasit, Ishraga E; Giha, Hayder A; Kachur, S Patrick; Lynch, Caroline; Rwakimari, John B; Chanda, Pascalina; Hawela, Moonga; Sharp, Brian; Naidoo, Inbarani; Roper, Cally

Reduced variation around drug-resistant dhfr alleles in African Plasmodium falciparum. (2005) Pearce, Richard; Malisa, Allen; Kachur, S Patrick; Barnes, Karen; Sharp, Brian; Roper, Cally

World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. (2007) Plowe, Christopher V; Roper, Cally; Barnwell, John W; Happi, Christian T; Joshi, Hema H; Mbacham, Wilfred; Meshnick, Steven R; Mugittu, Kefas; Naidoo, Inbarani; Price, Ric N; Shafer, Robert W; Sibley, Carol H; Sutherland, Colin J; Zimmerman, Peter A; Rosenthal, Philip J

PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation. (2013) Preston, Mark D; Assefa, Samuel A; Ocholla, Harold; Sutherland, Colin J; Borrmann, Steffen; Nzila, Alexis; Michon, Pascal; Hien, Tran Tinh; Bousema, Teun; Drakeley, Christopher J; Zongo, Issaka; Ouédraogo, Jean-Bosco; Djimde, Abdoulaye A; Doumbo, Ogobara K; Nosten, Francois; Fairhurst, Rick M; Conway, David J; Roper, Cally; Clark, Taane G

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. (2014) Preston, Mark D; Campino, Susana; Assefa, Samuel A; Echeverry, Diego F; Ocholla, Harold; Amambua-Ngwa, Alfred; Stewart, Lindsay B; Conway, David J; Borrmann, Steffen; Michon, Pascal; Zongo, Issaka; Ouédraogo, Jean-Bosco; Djimde, Abdoulaye A; Doumbo, Ogobara K; Nosten, Francois; Pain, Arnab; Bousema, Teun; Drakeley, Chris J; Fairhurst, Rick M; Sutherland, Colin J; Roper, Cally; Clark, Taane G

Five years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo Province, Southern Mozambique. (2010) Raman, Jaishree; Little, Francesca; Roper, Cally; Kleinschmidt, Immo; Cassam, Yasmin; Maharaj, Rajendra; Barnes, Karen I

Differential effect of regional drug pressure on dihydrofolate reductase and dihydropteroate synthetase mutations in southern Mozambique. (2008) Raman, Jaishree; Sharp, Brian; Kleinschmidt, Immo; Roper, Cally; Streat, Elizabeth; Kelly, Val; Barnes, Karen I

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi. (2016) Ravenhall, Matt; Benavente, Ernest Diez; Mipando, Mwapatsa; Jensen, Anja TR; Sutherland, Colin J; Roper, Cally; Sepúlveda, Nuno; Kwiatkowski, Dominic P; Montgomery, Jacqui; Phiri, Kamija S; Terlouw, Anja; Craig, Alister; Campino, Susana; Ocholla, Harold; Clark, Taane G

Stopping the spread of drug-resistant malaria - Response. (2004) Roper, C; Pearce, R; Nair, S; Sharp, B; Nosten, F; Anderson, T

Molecular surveillance for artemisinin resistance in Africa. (2014) Roper, Cally; Alifrangis, Michael; Ariey, Frederic; Talisuna, Ambrose; Menard, Didier; Mercereau-Puijalon, Odile; Ringwald, Pascal

Antifolate antimalarial resistance in southeast Africa: a population-based analysis. (2003) Roper, Cally; Pearce, Richard; Bredenkamp, Barry; Gumede, Jonathan; Drakeley, Chris; Mosha, Frank; Chandramohan, Daniel; Sharp, Brian

Intercontinental spread of pyrimethamine-resistant malaria. (2004) Roper, Cally; Pearce, Richard; Nair, Shalini; Sharp, Brian; Nosten, François; Anderson, Tim

Current issues for anti-malarial drugs to control P. falciparum malaria. (2006) Schellenberg, D; Abdulla, S; Roper, C

Analysis of polymorphisms in the merozoite surface protein-3α gene and two microsatellite loci in Sri Lankan Plasmodium vivax: evidence of population substructure in Sri Lanka. (2011) Schousboe, Mette L; Rajakaruna, Rupika S; Amerasinghe, Priyanie H; Konradsen, Flemming; Ord, Rosalynn; Pearce, Richard; Bygbjerg, Ib C; Roper, Cally; Alifrangis, Michael

Global and local genetic diversity at two microsatellite loci in Plasmodium vivax parasites from Asia, Africa and South America. (2014) Schousboe, Mette L; Ranjitkar, Samir; Rajakaruna, Rupika S; Amerasinghe, Priyanie H; Konradsen, Flemming; Morales, Francisco; Ord, Rosalynn; Pearce, Richard; Leslie, Toby; Rowland, Mark; Gadalla, Nahla; Bygbjerg, Ib C; Alifrangis, Michael; Roper, Cally html

Multiple Origins of Mutations in the mdr1 Gene--A Putative Marker of Chloroquine Resistance in P. vivax. (2015) Schousboe, Mette L; Ranjitkar, Samir; Rajakaruna, Rupika S; Amerasinghe, Priyanie H; Morales, Francisco; Pearce, Richard; Ord, Rosalyn; Leslie, Toby; Rowland, Mark; Gadalla, Nahla B; Konradsen, Flemming; Bygbjerg, Ib C; Roper, Cally; Alifrangis, Michael

Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes. (2006) Swarthout, TD; van den Broek, IV; Kayembe, G; Montgomery, J; Pota, H; Roper, C

Mitigating the threats of artemisinin resistance in Africa: Requirements for enhanced wide coverage malaria drug resistance surveillance and response systems. (2012) Talisuna, AO; Karema, C; Ogutu, B; Juma, E; Logedi, J; Nyandigisi, A; Mulenga, M; Mbacham, W; Roper, C; Guerin, P; Dalessandro, U; Snow., RW

In-vivo efficacy of amodiaquine-artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya. (2009) Thwing, JI; Odero, CO; Odhiambo, FO; Otieno, KO; Kariuki, S; Ord, R; Roper, C; McMorrow, M; Vulule, J; Slutsker, L; Newman, RD; Hamel, MJ; Desai, M

Monitoring antifolate resistance in intermittent preventive therapy for malaria. (2013) Venkatesan, Meera; Alifrangis, Michael; Roper, Cally; Plowe, Christopher V

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data. (2015) WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Gr; Adjuik, Martin A; Allan, Richard; Anvikar, Anupkumar R; Ashley, Elizabeth A; Ba, Mamadou S; Barennes, Hubert; Barnes, Karen I; Bassat, Quique; Baudin, Elisabeth; Björkman, Anders; Bompart, François; Bonnet, Maryline; Borrmann, Steffen; Brasseur, Philippe; Bukirwa, Hasifa; Checchi, Francesco; Cot, Michel; Dahal, Prabin; D'Alessandro, Umberto; Deloron, Philippe; Desai, Meghna; Diap, Graciela; Djimde, Abdoulaye A; Dorsey, Grant; Doumbo, Ogobara K; Espié, Emmanuelle; Etard, Jean-Francois; Fanello, Caterina I; Faucher, Jean-François; Faye, Babacar; Flegg, Jennifer A; Gaye, Oumar; Gething, Peter W; González, Raquel; Grandesso, Francesco; Guerin, Philippe J; Guthmann, Jean-Paul; Hamour, Sally; Hasugian, Armedy Ronny; Hay, Simon I; Humphreys, Georgina S; Jullien, Vincent; Juma, Elizabeth; Kamya, Moses R; Karema, Corine; Kiechel, Jean R; Kremsner, Peter G; Krishna, Sanjeev; Lameyre, Valérie; Ibrahim, Laminou M; Lee, Sue J; Lell, Bertrand; Mårtensson, Andreas; Massougbodji, Achille; Menan, Hervé; Ménard, Didier; Menéndez, Clara; Meremikwu, Martin; Moreira, Clarissa; Nabasumba, Carolyn; Nambozi, Michael; Ndiaye, Jean-Louis; Nikiema, Frederic; Nsanzabana, Christian; Ntoumi, Francine; Ogutu, Bernhards R; Olliaro, Piero; Osorio, Lyda; Ouédraogo, Jean-Bosco; Penali, Louis K; Pene, Mbaye; Pinoges, Loretxu; Piola, Patrice; Price, Ric N; Roper, Cally; Rosenthal, Philip J; Rwagacondo, Claude Emile; Same-Ekobo, Albert; Schramm, Birgit; Seck, Amadou; Sharma, Bhawna; Sibley, Carol Hopkins; Sinou, Véronique; Sirima, Sodiomon B; Smith, Jeffery J; Smithuis, Frank; Somé, Fabrice A; Sow, Doudou; Staedke, Sarah G; Stepniewska, Kasia; Swarthout, Todd D; Sylla, Khadime; Talisuna, Ambrose O; Tarning, Joel; Taylor, Walter RJ; Temu, Emmanuel A; Thwing, Julie I; Tjitra, Emiliana; Tine, Roger CK; Tinto, Halidou; Vaillant, Michel T; Valecha, Neena; Van den Broek, Ingrid; White, Nicholas J; Yeka, Adoke; Zongo, Issaka

Effect of Plasmodium falciparum sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive therapy for malaria in pregnancy in Africa: a systematic review and meta-analysis. (2019) van Eijk, Anna Maria; Larsen, David A; Kayentao, Kassoum; Koshy, Gibby; Slaughter, Douglas EC; Roper, Cally; Okell, Lucy C; Desai, Meghna; Gutman, Julie; Khairallah, Carole; Rogerson, Stephen J; Hopkins Sibley, Carol; Meshnick, Steven R; Taylor, Steve M; Ter Kuile, Feiko O

Markers of sulfadoxine-pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention. (2019) van Lenthe, Marit; van der Meulen, Renske; Lassovski, Maryvonne; Ouabo, Adelaide; Bakula, Edwige; Badio, Colette; Cibenda, Deogratias; Okell, Lucy; Piriou, Erwan; Grignard, Lynn; Lanke, Kjerstin; Rao, Bhargavi; Bousema, Teun; Roper, Cally

Conference or Workshop Item

The frequency of SP and CQ resistance markers in seven districts in Zambia. (2007) Hamainza, B; Hawella, M; Chanda, P; Porta, H; Mharakurwa, S; Roper, C; Sipilanyambe, N

Malaria genomics meets drug-resistance phenotyping in the field. (2009) Hunt, P; Macinnis, B; Roper, C

Collation and spatial mapping of pan-African antimalarial drug efficacy data. (2005) Naidoo, I; Roper, C; Sharp, BL

Dispersal of Drug Resistant DHPS Reveals Regional Migration Patterns among African Plasmodium Falciparum. (2008) Pearce, R; Roper, C

GENETIC DIVERSITY OF THE MEROZOITE SURFACE PROTEIN-3 alpha LOCUS IN PLASMODIUM VIVAX ISOLATES FROM SRI LANKA. (2008) Schousboe, ML; Rajakaruna, RS; Galappaththy, GN; Amerasinghe, PH; Konradsen, F; Roper, C; Bygbjerg, IC; Alifrangis, M

HIV, Gravidity and Malaria during Pregnancy in Southern Malawi: Antagonistic Interaction? (2008) Thwing, JI; Odero, C; Odhiambo, F; Kariuki, S; Roper, C; Ord, R; McMorrow, M; Kachur, SP; Slutsker, L; Vulule, J; Newman, R; Hamel, M; Desai, M

Thesis

Spatial and Temporal Analyses of Sulphadoxine Pyrimethamine Resistance in African Plasmodium falciparum malaria. (2015) Naidoo, I